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Demerol also known as Meperidine belongs to the class of medications known as narcotic analgesics (pain relievers). It is used to treat moderate-to-severe pain associated with many medical, surgical, obstetrical, and dental procedures. It works to decrease pain by acting on the brain to increase pain tolerance. Meperidine works very quickly and will usually begin to relieve pain within 15 minutes. This medication should not be used to treat chronic pain.
Pethidine is the most widely used opioid in labour and delivery but has fallen out of favour in some countries such as the United States in favour of other opioids, due to its potential drug interactions (especially with serotonergics) and its neurotoxic metabolite, norpethidine. It is still commonly used in the United Kingdom and New Zealandand was the preferred opioid in the United Kingdom for use during labour, but has been superseded somewhat by diamorphine (heroin) and other strong semi-synthetic opioids (e.g. hydromorphone) to avoid serotonin interactions since the mid-2000s.Pethidine is the preferred painkiller for diverticulitis, because it decreases intestinal intraluminal pressure.